DECIPHER Pooled Lentiviral shRNA Libraries

DECIPHER libraries are barcoded lentiviral shRNA libraries optimized for RNAi Genetic Screens in pooled format. They are made to cover nearly the entire annotated human gene set and most annotated mouse gene set. Lentiviral shRNA libraries were chosen over synthetic siRNA collections for their advantages in cancer research, specifically for the ability to efficiently transduce a range of cell types, including non-dividing cells, and for the highly effective long-term gene silencing. The pooled format screens follow a simple protocol and do not require access to expensive high-throughput arrayed screen equipment and infrastructure, putting large-scale pooled shRNA knockdown screens within reach of any researcher.

Please visit the Cellecta website for additional information on the DECIPHER shRNA Libraries.